First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-Lactamase | Zendy

María Virginia Villegas | Zendy; Karen Lolans | Zendy; Adriana Correa | Zendy; Juan Nicolás Kattán | Zendy; Jaime Alberto López | Zendy; John P. Quinn | Zendy

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First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-Lactamase

Author(s) -

María Virginia Villegas,

Karen Lolans,

Adriana Correa,

Juan Nicolás Kattán,

Jaime Alberto López,

John P. Quinn

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01405-06

Subject(s) - citrobacter freundii , imipenem , pseudomonas aeruginosa , microbiology and biotechnology , carbapenem , biology , enterobacteriaceae , beta lactamase , pseudomonadaceae , bacteria , antibiotic resistance , antibiotics , escherichia coli , gene , genetics

In Medellin, Colombia, threePseudomonas aeruginosa isolates with high-level carbapenem resistance (MIC ≥ 256 μg/ml) and an isolate ofCitrobacter freundii with reduced susceptibility to imipenem produced the plasmid-mediated class A carbapenemase KPC-2. This is the first report of a KPC-type β-lactamase identified outside of the familyEnterobacteriaceae .

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