Open AccessDevelopment and Validation of an In Vitro Resazurin-Based Susceptibility Assay against Madurella mycetomatis
Author(s) -
Shereen Abd Algaffar,
Annelies Verbon,
Wendy W. J. van de Sande,
Sami A. Khalid
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01338-20
Subject(s) - resazurin , microbiology and biotechnology , in vitro , biology , medicine , biochemistry
We present an in vitro susceptibility assay for Madurella mycetomatis hyphae using resazurin for endpoint reading. Using this assay, reproducible MICs were obtained for amphotericin B, itraconazole, voriconazole, posaconazole, terbinafine, and micafungin.
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