Two Clinical Strains of Klebsiella pneumoniae Carrying Plasmid-Borne bla IMP-4 , bla SHV-12 , and armA Isolated at a Pediatric Center in Shanghai, China | Zendy

Ying Liu | Zendy; Bei Zhang | Zendy; Qing Cao | Zendy; WeiChun Huang | Zendy; Lisong Shen | Zendy; Xuan Qin | Zendy

Open Access

Two Clinical Strains of Klebsiella pneumoniae Carrying Plasmid-Borne bla _IMP-4 , bla _SHV-12 , and armA Isolated at a Pediatric Center in Shanghai, China

Author(s) -

Ying Liu,

Bei Zhang,

Qing Cao,

WeiChun Huang,

Lisong Shen,

Xuan Qin

Publication year - 2009

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01325-08

Subject(s) - klebsiella pneumoniae , integron , plasmid , microbiology and biotechnology , biology , enterobacteriaceae , gene , genetics , escherichia coli

Two cases of pulmonary infection due to strains of multidrug-resistant Klebsiella pneumoniae were investigated. Beta-lactamase determinants, such as bla(IMP-4) and bla(SHV-12), and the 16S rRNA methyltransferase-encoding gene armA were detected in these plasmid-bearing organisms. The integron-borne bla(IMP-4) and armA contained intervening sequences highly related to those of a Vibrio cholerae O139 plasmid found in Hangzhou, China.

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