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In Vitro Interaction between Fluconazole and Triclosan against Clinical Isolates of Fluconazole-Resistant Candida albicans Determined by Different Methods
Author(s) -
Lu Yu,
Guanghui Ling,
Xuming Deng,
Jing Jin,
Qi Jin,
Na Guo
Publication year - 2011
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01313-10
Subject(s) - fluconazole , checkerboard , candida albicans , microbiology and biotechnology , broth microdilution , triclosan , agar , in vitro , biology , candida glabrata , fungi imperfecti , antifungal , minimum inhibitory concentration , medicine , antimicrobial , bacteria , biochemistry , genetics , pathology
The in vitro interaction between triclosan and fluconazole against 24 azole-resistant clinical isolates of Candida albicans was evaluated by the microdilution checkerboard technique. The synergisms were verified by time-killing curves and agar diffusion tests in selected strains. Antagonistic activity was not detected.

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