High Frequency of OXA-253-Producing Acinetobacter baumannii in Different Hospitals in Recife, Brazil
Author(s) -
Felipe Lira de Sá Cavalcanti,
Carina Lucena Mendes-Marques,
Crhisllane Rafaele dos Santos Vasconcelos,
Túlio de Lima Campos,
Antônio Mauro Rezende,
Danilo Elias Xavier,
Nilma Cintra Leal,
Osvaldo P. de Melo Neto,
Márcia Maria Camargo de Morais,
Tereza Cristina LealBalbino
Publication year - 2016
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01309-16
Subject(s) - acinetobacter baumannii , acinetobacter , microbiology and biotechnology , medicine , pseudomonas aeruginosa , biology , antibiotics , bacteria , genetics
Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with bla OXA-253 In all strains, the bla OXA-253 gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the bla OXA-253 gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.
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