English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Although much is known about vancomycin-resistant (VR)Enterococcus faecium , little is known about the epidemiology of VREnterococcus faecalis . The predilection of VRE. faecalis to transfer the vancomycin resistance determinant toStaphylococcus aureus is much greater than that of VRE. faecium . The epidemiology of VRE. faecalis has important implications regarding the emergence of vancomycin-resistantS. aureus (VRSA); 8 of 13 reported VRSA cases have been from Michigan. A retrospective case-case-control study was conducted at the Detroit Medical Center, located in southeastern Michigan. Unique patients with VRE. faecalis infection were matched to patients with strains of vancomycin-susceptible (VS)E. faecalis and to uninfected controls at a 1:1:1 ratio. Five hundred thirty-two VRE. faecalis cases were identified and were matched to 532 VSE. faecalis cases and 532 uninfected controls. The overall mean age of the study cohort (n = 1,596) was 63.0 ± 17.4 years, and 747 (46.8%) individuals were male. Independent predictors for the isolation of VRE. faecalis (but not VSE. faecalis ) compared to uninfected controls were an age of ≥65 years, nonhome residence, diabetes mellitus, peripheral vascular disease, exposure to cephalosporins and fluoroquinolones in the prior 3 months, and immunosuppressive status. Invasive procedures and/or surgery, chronic skin ulcers, and indwelling devices were risk factors for both VRE. faecalis and VSE. faecalis isolation. Cephalosporin and fluoroquinolone exposures were unique, independent predictors for isolation of VRE. faecalis . A majority of case patients had VRE. faecalis present at the time of admission. Control of VRE. faecalis , and ultimately VRSA, will likely require regional efforts focusing on infection prevention and antimicrobial stewardship.

Epidemiology of Vancomycin-Resistant Enterococcus faecalis: a Case-Case-Control Study