Increasing Genetic Relatedness of Ciprofloxacin-Resistant Streptococcus pneumoniae Isolated in Canada from 1997 to 2005 | Zendy

Kimberly A. Nichol | Zendy; Heather J. Adam | Zendy; James A. Karlowsky | Zendy; George G. Zhanel | Zendy; Daryl J. Hoban | Zendy

Open Access

Increasing Genetic Relatedness of Ciprofloxacin-Resistant Streptococcus pneumoniae Isolated in Canada from 1997 to 2005

Author(s) -

Kimberly A. Nichol,

Heather J. Adam,

James A. Karlowsky,

George G. Zhanel,

Daryl J. Hoban

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01260-07

Subject(s) - pulsed field gel electrophoresis , streptococcus pneumoniae , ciprofloxacin , microbiology and biotechnology , biology , gel electrophoresis , homogeneity (statistics) , genotype , streptococcaceae , genetics , gene , antibiotics , statistics , mathematics

The genetic relatedness of ciprofloxacin-resistantStreptococcus pneumoniae isolates collected from 1997 to 2002 (n = 82) and 2003 to 2005 (n = 123) was compared by pulsed-field gel electrophoresis (PFGE). Increased genetic homogeneity among the isolates from 2003 to 2005 (cluster analysis;P < 0.001) appeared to be due to expansion of existing clonal groups and to introduction of new PFGE types.

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