Therapeutic Challenges of Non- Aspergillus Invasive Mold Infections in Immunosuppressed Patients | Zendy

Frédéric Lamoth | Zendy; Dimitrios P. Kontoyiannis | Zendy

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Therapeutic Challenges of Non- Aspergillus Invasive Mold Infections in Immunosuppressed Patients

Author(s) -

Frédéric Lamoth,

Dimitrios P. Kontoyiannis

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01244-19

Subject(s) - aspergillosis , aspergillus , medicine , mold , immunosuppression , microbiology and biotechnology , virology , intensive care medicine , biology , immunology , genetics

WhileAspergillus spp. remain the major cause of invasive mold infections in hematologic cancer patients and transplant recipients, other opportunistic molds, such asMucorales ,Fusarium , andScedosporium spp. are increasingly encountered in an expanding population of patients with severe and prolonged immunosuppression. High potential for tissue invasion and dissemination, resistance to multiple antifungals and high mortality rates are hallmarks of these non-Aspergillus invasive mold infections (NAIMIs).

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