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Direct and Indirect Inhibition Effects of Resveratrol against Toxoplasma gondii Tachyzoites In Vitro
Author(s) -
Qiwei Chen,
Kai Dong,
Hanxiao Qin,
Yikai Yang,
Jinlei He,
Jiao Li,
Zhiwan Zheng,
Dali Chen,
Jianping Chen
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01233-18
Subject(s) - toxoplasma gondii , in vitro , resveratrol , microbiology and biotechnology , toxoplasmosis , protozoa , biology , chemistry , pharmacology , virology , immunology , biochemistry , antibody
Toxoplasma gondii is one of the most widespread obligatory parasitic protozoa and infects nearly all warm-blooded animals, leading to toxoplasmosis. The therapeutic drugs currently administered, like the combination of pyrimethamine and sulfadiazine, show high rates of toxic side effects, and drug resistance is encountered in some cases.

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