Open AccessInhibition of Chikungunya Virus Replication in Primary Human Fibroblasts by Liver X Receptor Agonist
Author(s) -
Jesse Hwang,
Yuchen Wang,
Erol Fikrig
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01220-19
Subject(s) - chikungunya , agonist , liver x receptor , virus , virology , viral replication , biology , interferon , inflammation , receptor , alphavirus , immunology , nuclear receptor , gene , genetics , transcription factor
The mosquito-borne chikungunya virus (CHIKV) causes acute pain and joint inflammation, and in recent years the virus has caused large epidemics in previously CHIKV-free geographic areas.
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