Dissemination of 16S rRNA Methylase ArmA-Producing Acinetobacter baumannii and Emergence of OXA-72 Carbapenemase Coproducers in Japan | Zendy

Tatsuya Tada | Zendy; Tohru MiyoshiAkiyama | Zendy; Kayo Shimada | Zendy; Masahiro Shimojima | Zendy; Teruo Kirikae | Zendy

Open Access

Dissemination of 16S rRNA Methylase ArmA-Producing Acinetobacter baumannii and Emergence of OXA-72 Carbapenemase Coproducers in Japan

Author(s) -

Tatsuya Tada,

Tohru MiyoshiAkiyama,

Kayo Shimada,

Masahiro Shimojima,

Teruo Kirikae

Publication year - 2014

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01212-13

Subject(s) - acinetobacter baumannii , biology , microbiology and biotechnology , 16s ribosomal rna , acinetobacter , genetics , antibiotics , gene , bacteria , pseudomonas aeruginosa

Forty-nine clinical isolates of multidrug-resistantAcinetobacter baumannii were obtained from 12 hospitals in 7 prefectures throughout Japan. Molecular phylogenetic analysis revealed the clonal spread ofA. baumannii sequence type 208 (ST208) and ST455 isolates harboring thearmA gene and ST512 harboring thearmA andbla OXA-72 genes. These findings show thatA. baumannii isolates harboringarmA are disseminated throughout Japan, and this is the first report to show thatA. baumannii strains harboringbla OXA-72 andarmA are emerging in hospitals in Japan.

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