Effect of Antibiotics on Staphylococcus aureus Producing Panton-Valentine Leukocidin | Zendy

Oana Dumitrescu | Zendy; Sandrine Boisset | Zendy; Cédric Badiou | Zendy; Michèle Bes | Zendy; Yvonne Benito | Zendy; M.E. Reverdy | Zendy; François Vandenesch | Zendy; Jérôme Étienne | Zendy; Gérard Lina | Zendy

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Effect of Antibiotics on Staphylococcus aureus Producing Panton-Valentine Leukocidin

Author(s) -

Oana Dumitrescu,

Sandrine Boisset,

Cédric Badiou,

Michèle Bes,

Yvonne Benito,

M.E. Reverdy,

François Vandenesch,

Jérôme Étienne,

Gérard Lina

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01201-06

Subject(s) - panton–valentine leukocidin , microbiology and biotechnology , staphylococcus aureus , antibiotics , leukocidin , staphylococcal infections , biology , methicillin resistant staphylococcus aureus , bacteria , genetics

We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.

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