Regulatory Mechanisms of the LuxS/AI-2 System and Bacterial Resistance | Zendy

Yang Wang | Zendy; Baobao Liu | Zendy; Daniel Grenier | Zendy; Li Yi | Zendy

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Regulatory Mechanisms of the LuxS/AI-2 System and Bacterial Resistance

Author(s) -

Yang Wang,

Baobao Liu,

Daniel Grenier,

Li Yi

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01186-19

Subject(s) - antibiotic resistance , microbiology and biotechnology , resistance (ecology) , biology , computational biology , antibiotics , ecology

The quorum-sensing (QS) system is an intercellular cell-cell communication mechanism that controls the expression of genes involved in a variety of cellular processes and that plays critical roles in the adaption and survival of bacteria in their environment. The LuxS/AI-2 QS system, which uses AI-2 (autoinducer-2) as a signal molecule, has been identified in both Gram-negative and Gram-positive bacteria.

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