Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions | Zendy

Boubakar Ba | Zendy; Karen Gaudin | Zendy; Amélie Désiré | Zendy; Thida Phoeung | Zendy; M. LANGLOIS | Zendy; Christian Behl | Zendy; Joel Unowsky | Zendy; Indravadan H. Patel | Zendy; A. Waseem Malick | Zendy; Melba Gomes | Zendy; Nicholas J. White | Zendy; Tina Kauss | Zendy

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Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions

Author(s) -

Boubakar Ba,

Karen Gaudin,

Amélie Désiré,

Thida Phoeung,

M. LANGLOIS,

Christian Behl,

Joel Unowsky,

Indravadan H. Patel,

A. Waseem Malick,

Melba Gomes,

Nicholas J. White,

Tina Kauss

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01170-18

Subject(s) - bioavailability , ceftriaxone , medicine , absorption (acoustics) , rectal administration , pharmacology , pharmacokinetics , sepsis , antibiotics , biology , microbiology and biotechnology , physics , acoustics

Neonatal sepsis is a major cause of infant mortality in developing countries because of delayed injectable treatment, making it urgent to develop noninjectable formulations that can reduce treatment delays in resource-limited settings. Ceftriaxone, available only for injection, needs absorption enhancers to achieve adequate bioavailability via nonparenteral administration.

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