Complete Nucleotide Sequences of mcr-4.3 -Carrying Plasmids in Acinetobacter baumannii Sequence Type 345 of Human and Food Origin from the Czech Republic, the First Case in Europe | Zendy

Ibrahim Bitar | Zendy; Matej Medvecký | Zendy; Tereza Gelbíčová | Zendy; Vladislav Jakubů | Zendy; Jaroslav Hrabák | Zendy; Helena Žemličková | Zendy; Renáta Karpíšková | Zendy; Monika Dolejská | Zendy

Open Access

Complete Nucleotide Sequences of mcr-4.3 -Carrying Plasmids in Acinetobacter baumannii Sequence Type 345 of Human and Food Origin from the Czech Republic, the First Case in Europe

Author(s) -

Ibrahim Bitar,

Matej Medvecký,

Tereza Gelbíčová,

Vladislav Jakubů,

Jaroslav Hrabák,

Helena Žemličková,

Renáta Karpíšková,

Monika Dolejská

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01166-19

Subject(s) - plasmid , acinetobacter baumannii , biology , czech , gene , complete sequence , microbiology and biotechnology , strain (injury) , genetics , nucleic acid sequence , sequence (biology) , bacteria , genome , linguistics , philosophy , anatomy , pseudomonas aeruginosa

Here, we describe two plasmids carryingmcr-4.3 in twoAcinetobacter baumannii strains isolated from imported food and a clinical sample. The comparative analysis of these plasmids, with two other plasmids reported in the NCBI database, highlighted the common origin of the plasmidic structure carryingmcr-4.3 . This is the first case of themcr-4.3 gene in aA. baumannii strain isolated from a clinical case in Europe. We hypothesize that food import is initiating the spread in Czech Republic.

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