Open AccessFirst Identification and Characterization of an AdeABC-Like Efflux Pump in Acinetobacter Genomospecies 13TU
Author(s) -
Ignasi Roca,
Paula Espinal,
Sara Martí,
Jordi Vila
Publication year - 2011
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01142-10
Subject(s) - efflux , microbiology and biotechnology , acinetobacter , identification (biology) , neisseriaceae , biology , computational biology , antibiotics , genetics , botany
Non-Acinetobacter baumannii spp. are emerging among clinicalAcinetobacter isolates causing nosocomial infections, and some (such as genomospecies 13TU) appear to be multidrug resistant. The prevalence of non-Acinetobacter baumannii spp. in the hospital setting is likely understated due to poor identification techniques. We report the first identification of an AdeABC-type efflux pump in anAcinetobacter genomospecies 13TU clinical isolate, its contribution to multidrug resistance, and the coexistence of three Ade-type efflux pumps in this strain.