Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006
Author(s) -
Éric Dannaoui,
Olivier Lortholary,
Dorothée Raoux,
M.-E. Bougnoux,
Gian Maria Galeazzi,
Christine Lawrence,
Didier Moissenet,
I. Poîlane,
Damien Hoinard,
Françoise Dromer
Publication year - 2007
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01140-07
Subject(s) - micafungin , caspofungin , candida krusei , candida tropicalis , candida glabrata , candida dubliniensis , candida parapsilosis , microbiology and biotechnology , candida albicans , echinocandins , yeast , biology , in vitro , antifungal , corpus albicans , amphotericin b , biochemistry
The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom