In Vitro Activities of Nine Antifungal Drugs against 81 Phialophora and Cyphellophora Isolates | Zendy

Peiying Feng | Zendy; Mohammad Javad Najafzadeh | Zendy; Jiufeng Sun | Zendy; Sarah Ahmed | Zendy; Liyan Xi | Zendy; Sybren de Hoog | Zendy; Lai Wei | Zendy; Chun Lu | Zendy; Corné H. W. Klaassen | Zendy; Jacques F. Meis | Zendy

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In Vitro Activities of Nine Antifungal Drugs against 81 Phialophora and Cyphellophora Isolates

Author(s) -

Peiying Feng,

Mohammad Javad Najafzadeh,

Jiufeng Sun,

Sarah Ahmed,

Liyan Xi,

Sybren de Hoog,

Lai Wei,

Chun Lu,

Corné H. W. Klaassen,

Jacques F. Meis

Publication year - 2012

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01112-12

Subject(s) - posaconazole , caspofungin , voriconazole , micafungin , itraconazole , terbinafine , amphotericin b , fluconazole , microbiology and biotechnology , biology , antifungal , in vitro , biochemistry

Cyphellophora guyanensis (n = 15), other Cyphellophora species (n = 11), Phialophora europaea (n = 43), and other Phialophora species (n = 12) were tested in vitro against nine antifungal drugs. The MIC(90)s across all of the strains (n = 81) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.5 μg/ml; voriconazole, 1 μg/ml; micafungin, 1 μg/ml; terbinafine, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 4 μg/ml; fluconazole, 8 μg/ml; amphotericin B, 16 μg/ml.

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