Synergistic Interaction between Silver Nanoparticles and Membrane-Permeabilizing Antimicrobial Peptides | Zendy

Serge Ruden | Zendy; Kai Hilpert | Zendy; Marina Berditsch | Zendy; Parvesh Wadhwani | Zendy; Anne S. Ulrich | Zendy

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Synergistic Interaction between Silver Nanoparticles and Membrane-Permeabilizing Antimicrobial Peptides

Author(s) -

Serge Ruden,

Kai Hilpert,

Marina Berditsch,

Parvesh Wadhwani,

Anne S. Ulrich

Publication year - 2009

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01106-08

Subject(s) - silver nanoparticle , antimicrobial , membrane , antimicrobial peptides , polymyxin , bacteria , chemistry , polymyxin b , nanoparticle , microbiology and biotechnology , nanotechnology , biochemistry , antibiotics , biology , materials science , genetics

Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects between polymyxin B and silver nanoparticles for gram-negative bacteria.

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