Screening the Saccharomyces cerevisiae Nonessential Gene Deletion Library Reveals Diverse Mechanisms of Action for Antifungal Plant Defensins | Zendy

Kathy Parisi | Zendy; Stephen R. Doyle | Zendy; Eunice Lee | Zendy; Rohan G. T. Lowe | Zendy; Nicole L. van der Weerden | Zendy; Marilyn A. Anderson | Zendy; Mark R. Bleackley | Zendy

Open Access

Screening the Saccharomyces cerevisiae Nonessential Gene Deletion Library Reveals Diverse Mechanisms of Action for Antifungal Plant Defensins

Author(s) -

Kathy Parisi,

Stephen R. Doyle,

Eunice Lee,

Rohan G. T. Lowe,

Nicole L. van der Weerden,

Marilyn A. Anderson,

Mark R. Bleackley

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01097-19

Subject(s) - saccharomyces cerevisiae , antifungal , gene , biology , genetics , action (physics) , mechanism of action , computational biology , microbiology and biotechnology , in vitro , physics , quantum mechanics

Plant defensins are a large family of proteins, most of which have antifungal activity against a broad spectrum of fungi. However, little is known about how they exert their activity. The mechanisms of action of only a few members of the family have been investigated and, in most cases, there are still a number of unknowns.

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