Promising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensis | Zendy

Franciele Abigail Vilugron Rodrigues-Vendramini | Zendy; Cidnei Marschalk | Zendy; Marina Toplak | Zendy; Peter Macheroux | Zendy; Patricia Mendonca | Zendy; Terezinha Inez Estivalet Svidzinski | Zendy; Flávio Augusto Vicente Seixas | Zendy; Érika Seki Kioshima | Zendy

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Promising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensis

Author(s) -

Franciele Abigail Vilugron Rodrigues-Vendramini,

Cidnei Marschalk,

Marina Toplak,

Peter Macheroux,

Patricia Mendonca,

Terezinha Inez Estivalet Svidzinski,

Flávio Augusto Vicente Seixas,

Érika Seki Kioshima

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01097-18

Subject(s) - paracoccidioides brasiliensis , microbiology and biotechnology , antifungal , biology

Paracoccidioidomycosis (PCM), caused byParacoccidioides , is a systemic mycosis with granulomatous character and a restricted therapeutic arsenal. The aim of this work was to search for new alternatives to treat largely neglected tropical mycosis, such as PCM.

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