Therapeutic Effects of Intravitreously Administered Bacteriophage in a Mouse Model of Endophthalmitis Caused by Vancomycin-Sensitive or -Resistant Enterococcus faecalis | Zendy

Tatsuma Kishimoto | Zendy; Waka Ishida | Zendy; Ken Fukuda | Zendy; Isakajima | Zendy; Takashi Suzuki | Zendy; Jumpei Uchiyama | Zendy; Shigenobu Matsuzaki | Zendy; Daisuke Todokoro | Zendy; Masanori Daibata | Zendy; Atsuki Fukushima | Zendy

Open Access

Therapeutic Effects of Intravitreously Administered Bacteriophage in a Mouse Model of Endophthalmitis Caused by Vancomycin-Sensitive or -Resistant Enterococcus faecalis

Author(s) -

Tatsuma Kishimoto,

Waka Ishida,

Ken Fukuda,

Isakajima,

Takashi Suzuki,

Jumpei Uchiyama,

Shigenobu Matsuzaki,

Daisuke Todokoro,

Masanori Daibata,

Atsuki Fukushima

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01088-19

Subject(s) - enterococcus faecalis , vancomycin , enterococcus , endophthalmitis , microbiology and biotechnology , bacteriophage , biology , medicine , antibiotics , bacteria , staphylococcus aureus , surgery , escherichia coli , biochemistry , gene , genetics

Endophthalmitis due to infection withEnterococcus spp. progresses rapidly and often results in substantial and irreversible vision loss. Given that the frequency of this condition caused by vancomycin-resistantEnterococcus faecalis has been increasing, the development of novel therapeutics is urgently required.

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