A Randomized Study of the Single-Dose Safety, Pharmacokinetics, and Food Effect of Chinfloxacin and Its Effect on Thorough QT/QTc Interval in Healthy Chinese Volunteers | Zendy

Caiyun Zhao | Zendy; Yuan Lv | Zendy; Min-Ji Wei | Zendy; Xiangyan Li | Zendy; Fang Hou | Zendy; Jin Wang | Zendy; Xuzhu Ma | Zendy; Zisheng Kang | Zendy; Wei Mao | Zendy; Yan Liu | Zendy; Ya-Hong Xia | Zendy; Jihong Tian | Zendy

Open Access

A Randomized Study of the Single-Dose Safety, Pharmacokinetics, and Food Effect of Chinfloxacin and Its Effect on Thorough QT/QTc Interval in Healthy Chinese Volunteers

Author(s) -

Caiyun Zhao,

Yuan Lv,

Min-Ji Wei,

Xiangyan Li,

Fang Hou,

Jin Wang,

Xuzhu Ma,

Zisheng Kang,

Wei Mao,

Yan Liu,

Ya-Hong Xia,

Jihong Tian

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01087-18

Subject(s) - qt interval , pharmacokinetics , medicine , confidence interval , randomized controlled trial , pharmacology , anesthesia

Chinfloxacin hydrochloride is a novel tricyclic fluorinated quinolone in development for treatment of conventional and biothreat infections. This first-in-human randomized study in Chinese healthy subjects was divided into 5 parts.

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