Correlation ofIn VitroSusceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris
Author(s) -
Ananta Khurana,
Aradhana Masih,
Anuradha Chowdhary,
Kabir Sardana,
Sagar Borker,
Aastha Gupta,
R. K. Gautam,
Pankaj Sharma,
Dhruv Jain
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01038-18
Subject(s) - squalene monooxygenase , terbinafine , itraconazole , dermatophyte , tinea capitis , microbiology and biotechnology , medicine , biology , voriconazole , antifungal , dermatology , gene , genetics , biosynthesis
Recalcitrant dermatophytoses are on the rise in India. High MICs of terbinafine (TRB) and squalene epoxidase (SQLE ) gene mutations conferring resistance inTrichophyton spp.
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