Antifungal Drug Susceptibility Profile of Pichia anomala Isolates from Patients Presenting with Nosocomial Fungemia | Zendy

Vânia Lúcia Ribeiro da Matta | Zendy; Márcia de Souza Carvalho Melhem | Zendy; Arnaldo Lopes Colombo | Zendy; Maria Luíza Moretti | Zendy; L Rodero | Zendy; Gisele Madeira Duboc de Almeida | Zendy; Marilena dos Anjos Martins | Zendy; Sílvia Figueiredo Costa | Zendy; Maria Beatriz G. Souza Dias | Zendy; Márcio Nucci | Zendy; Anna S. Levin | Zendy

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Antifungal Drug Susceptibility Profile of Pichia anomala Isolates from Patients Presenting with Nosocomial Fungemia

Author(s) -

Vânia Lúcia Ribeiro da Matta,

Márcia de Souza Carvalho Melhem,

Arnaldo Lopes Colombo,

Maria Luíza Moretti,

L Rodero,

Gisele Madeira Duboc de Almeida,

Marilena dos Anjos Martins,

Sílvia Figueiredo Costa,

Maria Beatriz G. Souza Dias,

Márcio Nucci,

Anna S. Levin

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01038-06

Subject(s) - fungemia , microbiology and biotechnology , antifungal , antifungal drugs , antifungal drug , drug resistance , drug , medicine , biology , pharmacology

In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.

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