Comparison between the EUCAST Procedure and the Etest for Determination of the Susceptibility of Candida Species Isolates to Micafungin | Zendy

Laura Judith Marcos-Zambrano | Zendy; Pilar Escribano | Zendy; Cristina Rueda | Zendy; Óscar Zaragoza | Zendy; Emilio Bouza | Zendy; Jesús Guinea | Zendy

Open Access

Comparison between the EUCAST Procedure and the Etest for Determination of the Susceptibility of Candida Species Isolates to Micafungin

Author(s) -

Laura Judith Marcos-Zambrano,

Pilar Escribano,

Cristina Rueda,

Óscar Zaragoza,

Emilio Bouza,

Jesús Guinea

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01032-13

Subject(s) - etest , micafungin , candida krusei , microbiology and biotechnology , candida albicans , candida glabrata , biology , antifungal , corpus albicans , fluconazole , antibiotics

We compared the ability of the EUCAST EDef 7.2 and the Etest to detect the susceptibility to micafungin of 160 Candida and non-Candida clinical isolates. Agreement was higher when Etest MICs were obtained after 24 h of incubation; essential agreement was 90%, and categorical agreement was >90%. False susceptibility was seen only for Candida krusei (10%), and false resistance was observed in 6% of the isolates, ranging from 2.6% (C. glabrata) to 13% (C. albicans).

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