Magnitude of Voriconazole Resistance in Clinical and Environmental Isolates of Aspergillus flavus and Investigation into the Role of Multidrug Efflux Pumps | Zendy

Raees A. Paul | Zendy; Shivaprakash M. Rudramurthy | Zendy; Manpreet Dhaliwal | Zendy; Pankaj Singh | Zendy; Anup Ghosh | Zendy; Harsimran Kaur | Zendy; Subhash Varma | Zendy; Ritesh Agarwal | Zendy; Arunaloke Chakrabarti | Zendy

Open Access

Magnitude of Voriconazole Resistance in Clinical and Environmental Isolates of Aspergillus flavus and Investigation into the Role of Multidrug Efflux Pumps

Author(s) -

Raees A. Paul,

Shivaprakash M. Rudramurthy,

Manpreet Dhaliwal,

Pankaj Singh,

Anup Ghosh,

Harsimran Kaur,

Subhash Varma,

Ritesh Agarwal,

Arunaloke Chakrabarti

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01022-18

Subject(s) - efflux , voriconazole , microbiology and biotechnology , biology , aspergillus flavus , multiple drug resistance , azole , broth microdilution , wild type , candida albicans , drug resistance , gene , mutant , genetics , minimum inhibitory concentration , antimicrobial , antifungal

The magnitude of azole resistance inAspergillus flavus and its underlying mechanism is obscure. We evaluated the frequency of azole resistance in a collection of clinical (n = 121) and environmental isolates (n = 68) ofA. flavus by the broth microdilution method.

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