Association of QnrB Determinants and Production of Extended-Spectrum β-Lactamases or Plasmid-Mediated AmpC β-Lactamases in Clinical Isolates of Klebsiella pneumoniae | Zendy

Hyunjoo Pai | Zendy; Miran Seo | Zendy; Tae Yeal Choi | Zendy

Open Access

Association of QnrB Determinants and Production of Extended-Spectrum β-Lactamases or Plasmid-Mediated AmpC β-Lactamases in Clinical Isolates of Klebsiella pneumoniae

Author(s) -

Hyunjoo Pai,

Miran Seo,

Tae Yeal Choi

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00841-06

Subject(s) - klebsiella pneumoniae , plasmid , microbiology and biotechnology , cephalosporin , biology , escherichia coli , enterobacteriaceae , klebsiella , gene , antibiotics , genetics

Clinical isolates ofEscherichia coli andKlebsiella pneumoniae producing extended-spectrum β-lactamases or plasmid-mediated AmpC β-lactamases were screened forqnrA andqnrB genes.QnrB was present in 54 of 54 DHA-1-producingK. pneumoniae isolates and 10 of 45 SHV-12-producing ones, suggesting that the distribution of plasmids conferring resistance to extended-spectrum cephalosporins and quinolones in clinical isolates ofK. pneumoniae is widespread.

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