Effects of Glutathione and Ascorbic Acid on Streptomycin Sensitivity of Escherichia coli | Zendy

Manish Goswami | Zendy; Suhas H. Mangoli | Zendy; Narendra Jawali | Zendy

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Effects of Glutathione and Ascorbic Acid on Streptomycin Sensitivity of Escherichia coli

Author(s) -

Manish Goswami,

Suhas H. Mangoli,

Narendra Jawali

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00779-06

Subject(s) - ascorbic acid , escherichia coli , streptomycin , glutathione , antioxidant , reactive oxygen species , chemistry , biochemistry , microbiology and biotechnology , biology , antibiotics , food science , enzyme , gene

We examined the effects of antioxidants and the role of reactive oxygen species (ROS) on the antibacterial action of aminoglycosides in Escherichia coli. We concluded that reduced streptomycin sensitivity in the presence of glutathione and ascorbic acid is not due to the antioxidant-mediated scavenging of ROS.

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