In Silico Typing and Comparative Genomic Analysis of IncFII K Plasmids and Insights into the Evolution of Replicons, Plasmid Backbones, and Resistance Determinant Profiles | Zendy

Dexi Bi | Zendy; Jiayi Zheng | Zendy; Junjie Li | Zendy; Zi-Ke Sheng | Zendy; Xingchen Zhu | Zendy; HongYu Ou | Zendy; Qianyu Li | Zendy; Qing Wei | Zendy

Open Access

In Silico Typing and Comparative Genomic Analysis of IncFII _K Plasmids and Insights into the Evolution of Replicons, Plasmid Backbones, and Resistance Determinant Profiles

Author(s) -

Dexi Bi,

Jiayi Zheng,

Junjie Li,

Zi-Ke Sheng,

Xingchen Zhu,

HongYu Ou,

Qianyu Li,

Qing Wei

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00764-18

Subject(s) - plasmid , klebsiella pneumoniae , replicon , biology , in silico , typing , genetics , genome , multilocus sequence typing , computational biology , escherichia coli , gene , genotype

IncFIIK plasmids are associated with the acquisition and dissemination of multiple-antimicrobial resistance inKlebsiella pneumoniae and often encountered in clinical isolates of this species. Since the phylogeny and evolution of IncFIIK plasmids remain unclear, here we performed large-scalein silico typing and comparative analysis of these plasmids in publicly available bacterial/plasmid genomes.

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