Nationwide Survey of CTX-M-Type Extended-Spectrum β-Lactamases among Klebsiella pneumoniae Isolates in Slovenian Hospitals | Zendy

K. Meško Meglič | Zendy; Simon Koren | Zendy; Marie-France Palepou | Zendy; E. Karisik | Zendy; David M. Livermore | Zendy; Rachel Pike | Zendy; Alenka Andlovic | Zendy; Samo Jeverica | Zendy; Veronika KrižanHergouth | Zendy; M. Müller-Premru | Zendy; Katja Seme | Zendy; Neil Woodford | Zendy

Open Access

Nationwide Survey of CTX-M-Type Extended-Spectrum β-Lactamases among Klebsiella pneumoniae Isolates in Slovenian Hospitals

Author(s) -

K. Meško Meglič,

Simon Koren,

Marie-France Palepou,

E. Karisik,

David M. Livermore,

Rachel Pike,

Alenka Andlovic,

Samo Jeverica,

Veronika KrižanHergouth,

M. Müller-Premru,

Katja Seme,

Neil Woodford

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00746-08

Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , plasmid , biology , beta lactamase , klebsiella , genotype , pulsed field gel electrophoresis , enterobacteriaceae , gene , virology , genetics , escherichia coli

Among 177 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates collected from 11 Slovenian hospitals in 2005 and 2006, 60 (34%), from eight hospitals, harbored genes for CTX-M enzymes, with bla(CTX-M-15) detected by sequencing. These 60 isolates comprised 11 pulsed-field gel electrophoresis-defined strains, with several clusters of closely related isolates. Plasmids encoding CTX-M-15 enzyme were highly transmissible.

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