Comparative In Vitro Activities of Torezolid (DA-7157) against Clinical Isolates of Aerobic and Anaerobic Bacteria in South Korea | Zendy

Jong Hwa Yum | Zendy; Sung Choi | Zendy; Dongeun Yong | Zendy; Yunsop Chong | Zendy; Weon Bin Im | Zendy; Dong-Kwon Rhee | Zendy; Kyungwon Lee | Zendy

Open Access

Comparative In Vitro Activities of Torezolid (DA-7157) against Clinical Isolates of Aerobic and Anaerobic Bacteria in South Korea

Author(s) -

Jong Hwa Yum,

Sung Choi,

Dongeun Yong,

Yunsop Chong,

Weon Bin Im,

Dong-Kwon Rhee,

Kyungwon Lee

Publication year - 2010

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00728-10

Subject(s) - microbiology and biotechnology , anaerobic exercise , anaerobic bacteria , bacteria , aerobic bacteria , biology , in vitro , physiology , biochemistry , genetics

Resistance of Gram-positive pathogens to first-line antimicrobial agents has been increasing in many parts of the world. We compared the in vitro activities of torezolid with those of other antimicrobial agents, including linezolid, against clinical isolates of major aerobic and anaerobic bacteria. Torezolid had an MIC(90) of ≤0.5 μg/ml for the Gram-positive bacterial isolates tested and was more potent than either linezolid or vancomycin.

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