Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus | Zendy

Jean Bernatchez | Zendy; Zunhua Yang | Zendy; Michael Coste | Zendy; Jerry Li | Zendy; Sungjun Beck | Zendy; Fulai Liu | Zendy; Alex E. Clark | Zendy; Zhe Zhu | Zendy; Lucas A. Luna | Zendy; Christal D. Sohl | Zendy; Byron W. Purse | Zendy; Rongshi Li | Zendy; Jair L. Siqueira-Neto | Zendy

Open Access

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Author(s) -

Jean Bernatchez,

Zunhua Yang,

Michael Coste,

Jerry Li,

Sungjun Beck,

Fulai Liu,

Alex E. Clark,

Zhe Zhu,

Lucas A. Luna,

Christal D. Sohl,

Byron W. Purse,

Rongshi Li,

Jair L. Siqueira-Neto

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00725-18

Subject(s) - zika virus , microcephaly , virology , medicine , virus , guillain barre syndrome , flavivirus , immunology , pediatrics

Zika virus (ZIKV) has been linked to the development of microcephaly in newborns, as well as Guillain-Barré syndrome. There are currently no drugs available to treat ZIKV infection, and accordingly, there is an unmet medical need for the discovery of new therapies.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research