OqxAB, a Quinolone and Olaquindox Efflux Pump, Is Widely Distributed among Multidrug-Resistant Klebsiella pneumoniae Isolates of Human Origin | Zendy

Federico Pérez | Zendy; Susan D. Rudin | Zendy; Steven H. Marshall | Zendy; Peter Coakley | Zendy; Liang Chen | Zendy; Barry N. Kreiswirth | Zendy; Philip N. Rather | Zendy; Andrea M. Hujer | Zendy; Philip Toltzis | Zendy; David van Duin | Zendy; David L. Paterson | Zendy; Robert A. Bonomo | Zendy

Open Access

OqxAB, a Quinolone and Olaquindox Efflux Pump, Is Widely Distributed among Multidrug-Resistant Klebsiella pneumoniae Isolates of Human Origin

Author(s) -

Federico Pérez,

Susan D. Rudin,

Steven H. Marshall,

Peter Coakley,

Liang Chen,

Barry N. Kreiswirth,

Philip N. Rather,

Andrea M. Hujer,

Philip Toltzis,

David van Duin,

David L. Paterson,

Robert A. Bonomo

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00725-13

Subject(s) - efflux , quinolone , microbiology and biotechnology , multiple drug resistance , klebsiella pneumoniae , antibiotics , biology , antibacterial agent , drug resistance , bacteria , enterobacteriaceae , escherichia coli , gene , genetics

Use of antibiotics among livestock contributes to the selection and dissemination of multidrug resistant (MDR) bacteria ([1][1]). Olaquindox and carbadox are quinoxaline derivatives with antibacterial properties that prevent dysentery and enhance weight gain in suckling pigs ([2][2]). Resistance to

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