Tolerance to the Glycopeptides Vancomycin and Teicoplanin in Coagulase-Negative Staphylococci | Zendy

Ingrid Bourgeois | Zendy; Martine PestelCaron | Zendy; JeanFrançois Lemeland | Zendy; Jean-Louis Pons | Zendy; François Caron | Zendy

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Tolerance to the Glycopeptides Vancomycin and Teicoplanin in Coagulase-Negative Staphylococci

Author(s) -

Ingrid Bourgeois,

Martine PestelCaron,

JeanFrançois Lemeland,

Jean-Louis Pons,

François Caron

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00719-06

Subject(s) - staphylococcus lugdunensis , teicoplanin , glycopeptide , coagulase , vancomycin , microbiology and biotechnology , cons , staphylococcus , biology , staphylococcus haemolyticus , staphylococcus aureus , antibiotics , bacteria , genetics , computer science , programming language

Tolerance to vancomycin and teicoplanin in 90 clinical isolates of coagulase-negative staphylococci (CoNS) was investigated by time-kill curve methodology. Only six strains, belonging to theStaphylococcus lugdunensis species, exhibited tolerance. The seven otherS. lugdunensis strains tested displayed weak susceptibility to the bactericidal activity of glycopeptides compared to the other CoNS. These phenomena are of concern, sinceS. lugdunensis is recognized as one of the most pathogenic CoNS.

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