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In a previous study, mutants with enhanced ciprofloxacin resistance (Cipr ) were selected fromEscherichia coli J53/pMG252 carryingqnrA1 . Strain J53 Cipr 8-2 showed an increase in the copy number and transcription level ofqnrA1 . We sequenced the plasmids on Illumina and MinION platforms.

Multiple Copies of qnrA1 on an IncA/C 2 Plasmid Explain Enhanced Quinolone Resistance in an Escherichia coli Mutant

Multiple Copies of qnrA1 on an IncA/C ₂ Plasmid Explain Enhanced Quinolone Resistance in an Escherichia coli Mutant