First Report of the Multiresistance Gene cfr in Streptococcus suis | Zendy

Yang Wang | Zendy; Dexi Li | Zendy; Li Song | Zendy; Yang Liu | Zendy; Tao He | Zendy; Hebing Liu | Zendy; Congming Wu | Zendy; Štefan Schwarz | Zendy; Jianzhong Shen | Zendy

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First Report of the Multiresistance Gene cfr in Streptococcus suis

Author(s) -

Yang Wang,

Dexi Li,

Li Song,

Yang Liu,

Tao He,

Hebing Liu,

Congming Wu,

Štefan Schwarz,

Jianzhong Shen

Publication year - 2013

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00713-13

Subject(s) - amplicon , streptococcus suis , plasmid , biology , gene , microbiology and biotechnology , virology , streptococcaceae , sequence (biology) , genetics , polymerase chain reaction , virulence , antibiotics

The multiresistance genecfr was identified for the first time in streptococci, namely, in porcineStreptococcus suis isolate S10. Thecfr gene was detected on the ∼100-kb plasmid pStrcfr, where it was bracketed by two copies of the novel insertion sequence ISEnfa5 , located in the same orientation. The detection of acfr - and ISEnfa5 -containing amplicon by inverse PCR suggests that ISEnfa5 may play a role in the dissemination ofcfr .

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