TEM-184, a Novel TEM-Derived Extended-Spectrum β-Lactamase with Enhanced Activity against Aztreonam | Zendy

Alessandra Piccirilli | Zendy; Mariagrazia Perilli | Zendy; Gianfranco Amicosante | Zendy; Viola Conte | Zendy; Carlo Tascini | Zendy; Gian María Rossolini | Zendy; Tommaso Giani | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

TEM-184, a Novel TEM-Derived Extended-Spectrum β-Lactamase with Enhanced Activity against Aztreonam

Author(s) -

Alessandra Piccirilli,

Mariagrazia Perilli,

Gianfranco Amicosante,

Viola Conte,

Carlo Tascini,

Gian María Rossolini,

Tommaso Giani

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00688-18

Subject(s) - aztreonam , escherichia coli , microbiology and biotechnology , strain (injury) , enterobacteriaceae , broad spectrum , beta lactamase , biology , chemistry , antibiotics , genetics , antibiotic resistance , imipenem , combinatorial chemistry , gene , anatomy

TEM-184, a novel TEM-derived extended-spectrum β-lactamase (ESBL), was isolated from anEscherichia coli ST354 clinical strain. Compared to TEM-1, TEM-184 contains the mutations Q6K, E104K, I127V, R164S, and M182T.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research