Open AccessMetallo-β-Lactamase Gene bla IMP-15 in a Class 1 Integron, In 95 , from Pseudomonas aeruginosa Clinical Isolates from a Hospital in Mexico
Author(s) -
Ulises Garza–Ramos,
Rayo MorfínOtero,
Hélio S. Sader,
Ronald N. Jones,
Eva Hernández,
Eduardo Rodríguez Noriega,
Alejandro Sánchez,
Berta Carrillo,
Sergio Esparza-Ahumada,
Jesús Silva-Sánchez
Publication year - 2008
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00679-07
Subject(s) - integron , pseudomonas aeruginosa , gene cassette , microbiology and biotechnology , beta lactamase , plasmid , biology , pseudomonadaceae , pseudomonadales , antibacterial agent , gene , carbapenem , bacteria , virology , antibiotics , genetics , antibiotic resistance , escherichia coli
During 2003, 40 carbapenem-resistantPseudomonas aeruginosa clinical isolates collected in a Mexican tertiary-care hospital were screened for metallo-β-lactamase production. Thirteen isolates produced IMP-15, and 12 had a single pulsed-field gel electrophoresis pattern. Thebla IMP-15 gene cassette was inserted in a plasmid-borne integron with a unique array of gene cassettes and was named In95 .