In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6)Quinolone | Zendy

Kaori Tanaka | Zendy; Hiroshige Mikamo | Zendy; Ken'ichi Nakao | Zendy; Kunitomo Watanabe | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6)Quinolone

Author(s) -

Kaori Tanaka,

Hiroshige Mikamo,

Ken'ichi Nakao,

Kunitomo Watanabe

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00639-06

Subject(s) - imipenem , microbiology and biotechnology , bacteroides , quinolone , fusobacterium , in vitro , anaerobic bacteria , prevotella , chemistry , actinomyces , antibiotics , biology , bacteria , biochemistry , antibiotic resistance , genetics

Thein vitro activity of DX-619, a new des-F(6) quinolone, againstanaerobic bacteria was evaluated. DX-619 showed potent activity againstBacteroides ,Prevotella ,Fusobacterium ,Micromonas ,Actinomyces , andClostridium spp., with MIC50 s/MIC90 s of ≤0.03 to0.25/≤0.03 to 1 μg/ml, respectively. DX-619 was alsoactive against imipenem-resistantBacteroides spp., withMIC50 s/MIC90 s of 0.25/1 μg/ml,respectively.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research