The Repurposed Drug Disulfiram Inhibits Urease and Aldehyde Dehydrogenase and Prevents In Vitro Growth of the Oomycete Pythium insidiosum | Zendy

Theerapong Krajaejun | Zendy; Tassanee Lohnoo | Zendy; Wanta Yingyong | Zendy; Thidarat Rujirawat | Zendy; Yothin Kumsang | Zendy; Passara Jongkhajornpong | Zendy; Sirin Theerawatanasirikul | Zendy; Weerayuth Kittichotirat | Zendy; Onrapak Reamtong | Zendy; Hanna Yolanda | Zendy

Open Access

The Repurposed Drug Disulfiram Inhibits Urease and Aldehyde Dehydrogenase and Prevents In Vitro Growth of the Oomycete Pythium insidiosum

Author(s) -

Theerapong Krajaejun,

Tassanee Lohnoo,

Wanta Yingyong,

Thidarat Rujirawat,

Yothin Kumsang,

Passara Jongkhajornpong,

Sirin Theerawatanasirikul,

Weerayuth Kittichotirat,

Onrapak Reamtong,

Hanna Yolanda

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00609-19

Subject(s) - disulfiram , oomycete , microbiology and biotechnology , aldehyde dehydrogenase , antimicrobial , biology , pharmacology , pathogen , biochemistry , enzyme

Pythium insidiosum is an oomycete microorganism that causes a life-threatening infectious disease, called pythiosis, in humans and animals. The disease has been increasingly reported worldwide.

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