In Vitro Activity of Tomopenem (CS-023/RO4908463) against Anaerobic Bacteria | Zendy

Kaori Tanaka | Zendy; Hiroshige Mikamo | Zendy; Ken'ichi Nakao | Zendy; Taku Ichiishi | Zendy; Takatsugu Goto | Zendy; Yuka Yamagishi | Zendy; Kunitomo Watanabe | Zendy

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In Vitro Activity of Tomopenem (CS-023/RO4908463) against Anaerobic Bacteria

Author(s) -

Kaori Tanaka,

Hiroshige Mikamo,

Ken'ichi Nakao,

Taku Ichiishi,

Takatsugu Goto,

Yuka Yamagishi,

Kunitomo Watanabe

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00595-08

Subject(s) - doripenem , meropenem , carbapenem , microbiology and biotechnology , in vitro , bacteria , pharmacology , chemistry , antibiotics , biology , medicine , biochemistry , antibiotic resistance , genetics

The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC90 , 0.06 to 4 μg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.

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