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In Vitro Susceptibility of Burkholderia cepacia Complex Isolated from Cystic Fibrosis Patients to Ceftazidime-Avibactam and Ceftolozane-Tazobactam
Author(s) -
Annelien Van Dalem,
Margaux Herpol,
Fedoua Echahidi,
Charlotte Peeters,
Ingrid Wybo,
Elke De Wachter,
Peter Vandamme,
Denis Piérard
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00590-18
Subject(s) - ceftazidime/avibactam , burkholderia cepacia complex , cystic fibrosis , burkholderia , microbiology and biotechnology , ceftazidime , avibactam , antibiotics , trimethoprim , medicine , in vitro , sulfamethoxazole , biology , pseudomonas aeruginosa , bacteria , genetics , biochemistry
We tested thein vitro susceptibility of ceftazidime-avibactam and ceftolozane-tazobactam and 13 other antibiotics against 91Burkholderia cepacia complex (BCC) strains isolated from cystic fibrosis patients since 2012. The highest susceptibility (82%) was found for trimethoprim-sulfamethoxazole.

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