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Identification of 16S rRNA Methylase-Producing Acinetobacter baumannii Clinical Strains in North America
Author(s) -
Yohei Doi,
Jennifer Adams,
Kunikazu Yamane,
David L. Paterson
Publication year - 2007
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00560-07
Subject(s) - acinetobacter baumannii , microbiology and biotechnology , biology , identification (biology) , 16s ribosomal rna , acinetobacter , ribosomal rna , neisseriaceae , bacteria , antibiotics , genetics , pseudomonas aeruginosa , gene , botany
Five highly amikacin-resistant Acinetobacter baumannii isolates were collected at a medical center in Pennsylvania. The aminoglycoside resistance was due to the production of the 16S rRNA methylase ArmA. Two of the isolates coproduced OXA-23 beta-lactamase and were highly resistant to carbapenems as well. The isolates were genetically closely related by pulsed-field gel electrophoresis.

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