Simplified Testing Method for Direct Detection of Carbapenemase-Producing Organisms from Positive Blood Cultures Using the NG-Test Carba 5 Assay | Zendy

Liliana Giordano | Zendy; Barbara Fiori | Zendy; Tiziana D’Inzeo | Zendy; Gabriella Parisi | Zendy; Flora Marzia Liotti | Zendy; Giulia Menchinelli | Zendy; Giulia De Angelis | Zendy; Flavio De Maio | Zendy; Francesco Luzzaro | Zendy; Maurizio Sanguinetti | Zendy; Brunella Posteraro | Zendy; Teresa Spanu | Zendy

Open Access

Simplified Testing Method for Direct Detection of Carbapenemase-Producing Organisms from Positive Blood Cultures Using the NG-Test Carba 5 Assay

Author(s) -

Liliana Giordano,

Barbara Fiori,

Tiziana D’Inzeo,

Gabriella Parisi,

Flora Marzia Liotti,

Giulia Menchinelli,

Giulia De Angelis,

Flavio De Maio,

Francesco Luzzaro,

Maurizio Sanguinetti,

Brunella Posteraro,

Teresa Spanu

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00550-19

Subject(s) - false positive paradox , microbiology and biotechnology , blood culture , biology , enterobacteriaceae infections , chromatography , enterobacteriaceae , chemistry , antibiotics , escherichia coli , gene , mathematics , genetics , statistics

We directly tested 484 organisms from clinical (n = 310) and simulated (n = 174) positive blood cultures using the NG-Test Carba 5 assay for carbapenemase-producingEnterobacterales detection. The assay identified all but 4 of the KPC (170/171), OXA-48-like (22/22), VIM (19/21), and NDM (14/15) producers with no false positives.

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