Open AccessSingle-Center Pharmacokinetic Study and Simulation of a Low Meropenem Concentration in Brain-Dead Organ Donors
Author(s) -
Jae Myeong Lee,
Joo Won Lee,
Tae Seok Jeong,
Eun Sook Bang,
So Hee Kim
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00542-18
Subject(s) - meropenem , pharmacokinetics , volume of distribution , ertapenem , medicine , dose , pharmacology , regimen , antibacterial agent , carbapenem , anesthesia , antibiotics , chemistry , surgery , antibiotic resistance , biochemistry
Meropenem is an ultrabroad-spectrum antibiotic of the carbapenem family. In brain-dead organ donors, administration of standard meropenem dosages does not reach therapeutic levels.
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