Trailing or Paradoxical Growth of Candida albicans When Exposed to Caspofungin Is Not Associated with Microsatellite Genotypes | Zendy

Mohamed Khlif | Zendy; Hervé Bogreau | Zendy; A. Michel-Nguyen | Zendy; Ali Ayadi | Zendy; Stéphane Ranque | Zendy

Open Access

Trailing or Paradoxical Growth of Candida albicans When Exposed to Caspofungin Is Not Associated with Microsatellite Genotypes

Author(s) -

Mohamed Khlif,

Hervé Bogreau,

A. Michel-Nguyen,

Ali Ayadi,

Stéphane Ranque

Publication year - 2010

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00530-09

Subject(s) - caspofungin , genotype , candida albicans , biology , microsatellite , microbiology and biotechnology , fluconazole , genetics , antifungal , allele , gene

Multilocus microsatellite polymorphisms in 27 clinicalCandida albicans isolates were found to be clearly unrelated toin vitro paradoxical growth or trailing effect with caspofungin. These findings suggest that suchin vitro phenotypes are either gained or lost too rapidly to be predicted by more stable genomic markers.

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