Open AccessTrailing or Paradoxical Growth of Candida albicans When Exposed to Caspofungin Is Not Associated with Microsatellite Genotypes
Author(s) -
Mohamed Salah Khlif,
Hervé Bogreau,
A. Michel-Nguyen,
A. Àyadi,
Stéphane Ranque
Publication year - 2010
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00530-09
Subject(s) - caspofungin , genotype , candida albicans , biology , microsatellite , microbiology and biotechnology , fluconazole , genetics , antifungal , allele , gene
Multilocus microsatellite polymorphisms in 27 clinicalCandida albicans isolates were found to be clearly unrelated toin vitro paradoxical growth or trailing effect with caspofungin. These findings suggest that suchin vitro phenotypes are either gained or lost too rapidly to be predicted by more stable genomic markers.