In Vitro Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus , Including Heterogeneously Glycopeptide-Resistant Strains | Zendy

B. M. W. Diederen | Zendy; Inge van Duijn | Zendy; Piet Willemse | Zendy; Jan Kluytmans | Zendy

Open Access

In Vitro Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus , Including Heterogeneously Glycopeptide-Resistant Strains

Author(s) -

B. M. W. Diederen,

Inge van Duijn,

Piet Willemse,

Jan Kluytmans

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00526-06

Subject(s) - daptomycin , glycopeptide , etest , microbiology and biotechnology , staphylococcus aureus , methicillin resistant staphylococcus aureus , vancomycin , micrococcaceae , in vitro , biology , antibacterial agent , medicine , antibiotics , bacteria , biochemistry , genetics

The purpose of the present study was to assess the in vitro activity of daptomycin against a well-defined collection of methicillin-resistantStaphylococcus aureus (MRSA) isolates (n = 98), including heterogeneously glycopeptide-resistant MRSA (hGISA) strains. Susceptibility testing was performed by using the Etest system. Daptomycin was potent against both glycopeptide-susceptible and hGISA strains.

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