Endocarditis Caused by Highly Penicillin-Resistant Viridans Group Streptococci: Still Room for Vancomycin-Based Regimens | Zendy

Juan M. Pericàs | Zendy; Ruvandhi R. Nathavitharana | Zendy; C. García-de-la-Mària | Zendy; Carlos Falces | Zendy; Juan Ambrosioni | Zendy; Manel Almela | Zendy; Javier GarcíaGonzález | Zendy; Eduard Quintana | Zendy; Francesc Marco | Zendy; Asunción Moreno | Zendy; Arnold S. Bayer | Zendy; José M. Miró | Zendy; Adolf W. Karchmer | Zendy; Adrián Téllez | Zendy; Marta HernándezMeneses | Zendy; Delia García-Pares | Zendy; Cristina García de la Mària | Zendy; Javier Garcia-González | Zendy; Climent CasalsPascual | Zendy; Jordi Vilà | Zendy; Elena Sandoval | Zendy; Juan C. Paré | Zendy; Daniel Pereda | Zendy; Ramón Cartañá | Zendy; Salvador Pié i Ninot | Zendy; Manel Azqueta | Zendy; Marta Sitges | Zendy; Bárbara Vidal | Zendy; José Luís Pomar | Zendy; Manuel Castellá | Zendy; José Marı́a Tolosana | Zendy; José Ortíz | Zendy; Guillermina Fita | Zendy; Irene Rovira | Zendy; David Fuster | Zendy; José Ramírez | Zendy; Merçè Brunet | Zendy; Dolors Soy | Zendy; Pedro Castro | Zendy; Jaume Llopis | Zendy

Open Access

Endocarditis Caused by Highly Penicillin-Resistant Viridans Group Streptococci: Still Room for Vancomycin-Based Regimens

Author(s) -

Juan M. Pericàs,

Ruvandhi R. Nathavitharana,

C. García-de-la-Mària,

Carlos Falces,

Juan Ambrosioni,

Manel Almela,

Javier GarcíaGonzález,

Eduard Quintana,

Francesc Marco,

Asunción Moreno,

Arnold S. Bayer,

José M. Miró,

Adolf W. Karchmer,

Adrián Téllez,

Marta HernándezMeneses,

Delia García-Pares,

Cristina García de la Mària,

Javier Garcia-González,

Climent CasalsPascual,

Jordi Vilà,

Elena Sandoval,

Juan C. Paré,

Daniel Pereda,

Ramón Cartañá,

Salvador Pié i Ninot,

Manel Azqueta,

Marta Sitges,

Bárbara Vidal,

José Luís Pomar,

Manuel Castellá,

José Marı́a Tolosana,

José Ortíz,

Guillermina Fita,

Irene Rovira,

David Fuster,

José Ramírez,

Merçè Brunet,

Dolors Soy,

Pedro Castro,

Jaume Llopis

Publication year - 2019

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00516-19

Subject(s) - viridans streptococci , penicillin , endocarditis , vancomycin , infective endocarditis , antibiotics , microbiology and biotechnology , medicine , streptococcus , staphylococcus aureus , biology , bacteria , genetics

Optimal treatment options remain unknown for infective endocarditis (IE) caused by penicillin-resistant (PEN-R) viridans group streptococcal (VGS) strains. The aims of this study were to report two cases of highly PEN-R VGS IE, perform a literature review, and evaluate various antibiotic combinationsin vitro andin vivo .

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