Multidrug-Resistant Acinetobacter baumannii Chloramphenicol Resistance Requires an Inner Membrane Permease
Author(s) -
A. Karalewitz,
Samuel I. Miller
Publication year - 2018
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00513-18
Subject(s) - acinetobacter baumannii , microbiology and biotechnology , multiple drug resistance , chloramphenicol , bacterial outer membrane , biology , permease , acinetobacter , antibiotics , drug resistance , gram negative bacteria , polymyxin , bacteria , escherichia coli , pseudomonas aeruginosa , gene , genetics
Acinetobacter baumannii is a Gram-negative organism that is a cause of hospital-acquired multidrug-resistant (MDR) infections.A. baumannii has a unique cell surface compared to those of many other Gram-negative pathogens in that it can live without lipopolysaccharide (LPS) and it has a high content of cardiolipin in the outer membrane.
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